Febrile Neutropenia (FN) is a severe side effect of cancer treatment. The current investigation sought to uncover risk variables for reported infection in paediatric FN and cancer patients. From 2016 to 2018, patients under the age of 18 were included in this prospective cohort research. The Centers for Disease Control and Prevention standards were used to determine infection. There were 172 febrile neutropenic events investigated in all. Univariate analysis revealed the following risk factors: female gender; monocyte count 100 cell/mm, platelets 50,000, C-reactive protein (CRP) >90 mg/90dl, and hemoglobin 7 mg/7dl at the commencement of an episode; two or more episodes of FN, and fever onset; positive blood culture at fever onset. According to the multivariate analysis, the following variables were independent risk factors: CRP at the outset of a febrile episode > 90 mg/90dl, fever onset, and first positive blood culture. The lowest risk of infection was associated with the first episode and platelets more than 50,000 at the beginning of fever. A CRP >90 at the onset of a febrile episode, platelets 50,000, second episode or more, first fever episode during hospitalization, and positive first blood culture were found to be associated with a higher risk of infection and could be useful for establishing risk scores for infection in neutropenic children.
