Due to its impact on several organ systems, lupus is a chronic inflammatory autoimmune disease with a wide spectrum of clinical manifestations. Neonatal, discoid, drug-induced, and Systemic Lupus Erythematosus (SLE), which affects the majority of patients, are the four basic kinds of lupus. Due to aberrant immunological function, the development of autoantibodies, and the subsequent generation of immune complexes that may negatively impact healthy tissue, patients with lupus have a loss of self-tolerance.